Eugene L. Gottlieb

Eugene Garfield

Thisessaydiscusseslupus, an imnnme-systemdysfunctionthat affects may, especiallyyoung women, but is recognized by all too few. Its multiple manifestations have been baffling to researchers for over 100years; only rexently have the tools of molecular biology and immunogenetics reveafed substantial new information on its mechanism of autoimmunity. Still, the ukimate trigger for lupus remains a my...

Current Comments ” I EUGENE

Anyone growing up in a city, especially in tenements, has encountered cockroaches. From childhood I remember my mother clobbering them with a shoe or a newspaper. Looking back, I marvel at how mothers in slums managed to keep apartments free of them. Even in modem high rises, these inseets are indefatigable--often outwitting regulas extermination squads. However, what I encountered as a child w...

Current Comments ” EUGENE

Mew-analyses and their proper place in medical literature are explained along with how they differ fromtraditional literature reviews. Both the qualitative and quantitative amccts of meta-analvsis are consid-ered in relation to studying the results of clinical tri This issue [1 February 1991] includes ameta-analysis of the use of steroids in treat-ing chronic obstructive pulmona...

The Eugene Rasmusson Symposium

With Gottlieb beyond Gottlieb: The Role of Epigenetics in Psychobiological Development

The emerging field of molecular epigenetics studies relatively stable changes in genetic activity that are not due to changes in the DNA sequence. Initial research results indicate a functional role for epigenetic mechanisms in neuron development and neuronal cell function. However, concepts that integrate these findings in an overall theory of psychobiological development have yet to be develo...